Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer.

doi:10.1002/ijc.31548

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Article

Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer.

International journal of cancer - 1 Oct 2018

Diquigiovanni Chiara, Bergamini Christian, Evangelisti Cecilia, Isidori Federica, Vettori Andrea, Tiso Natascia, Argenton Francesco, Costanzini Anna, Iommarini Luisa, Anbunathan Hima, Pagotto Uberto, Repaci Andrea, Babbi Giulia, Casadio Rita, Lenaz Giorgio, Rhoden Kerry J, Porcelli Anna Maria, Fato Romana, Bowcock Anne, Seri Marco, Romeo Giovanni, Bonora Elena

Abstract excerpt

Familial aggregation is a significant risk factor for the development of thyroid cancer and familial non-medullary thyroid cancer (FNMTC) accounts for 5-7% of all NMTC. Whole exome sequencing analysis in the family affected by FNMTC with oncocytic features where our group previously identified a predisposing locus on chromosome 19p13.2, revealed a novel heterozygous mutation (c.400G > A, NM_012335; p.Gly134Ser)...

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PMID: 29672841
DOI: 10.1002/ijc.31548

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