Article
TTN mutations predict a poor prognosis in patients with thyroid cancer.
Bioscience reports - 29 Jul 2022
Han Xiudan, Chen Jianrong, Wang Jiao, Xu Jixiong, Liu Ying
Abstract excerpt
OBJECTIVE: We aimed to investigate the relationship between titin (TTN) gene mutations and thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential prognostic indicator of THCA. METHODS: From TCGA-THCA cohort, we performed a series of analyses to evaluate the prognostic value and potential mechanism of TTN in THCA. These patients were divided into the mutant-type (MUT) group and the...
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