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Article

Genomic and Transcriptomic Characterization of Sporadic Medullary Thyroid Carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Jul 2020

Qu Ning, Shi Xiao, Zhao Jing-Jing, Guan Haixia, Zhang Ting-Ting, Wen Shi-Shuai, Liao Tian, Hu Jia-Qian, Liu Wei-Yan, Wang Yu-Long, Huang Shenglin, Shi Rong-Liang, Wang Yu, Ji Qing-Hai

Abstract excerpt

Background: Sporadic medullary thyroid carcinoma (MTC) is a relatively uncommon neuroendocrine malignancy and the molecular tumorigenesis of its sporadic type (sMTC) is only partially understood. In this study, we performed a study focusing on the genomic and transcriptomic characterization of sMTC. Methods: Twenty-nine sMTC patients were included. Whole-exome sequencing (WES) was carried out in 18 patients,...

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Adolescent
Aged
Carcinoma, Medullary
Exome Sequencing
Proto-Oncogene Proteins c-ret

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thyroid Neoplasms

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PMID: 32031055
DOI: 10.1089/thy.2019.0531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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