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Article

Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets.

Psychiatric genetics - 1 Aug 2018

Curtis David

Abstract excerpt

BACKGROUND: The polygenic risk score (PRS) is derived from single nucleotide polymorphisms (SNPs) including those that are genome-wide significant and also including a large number of others more weakly associated with schizophrenia. Such variants are widely dispersed, though concentrated near genes expressed in the brain, and it has been proposed that these SNP associations result from impacts on cell regulatory...

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Identifiers

PMID: 29672343
DOI: 10.1097/YPG.0000000000000197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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