Article
Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features.
Genes - 12 Jul 2021
Yu Alice W, Peery J David, Won Hyejung
Abstract excerpt
Schizophrenia is a polygenic disorder with many genomic regions contributing to schizophrenia risk. The majority of genetic variants associated with schizophrenia lie in the non-coding genome and are thought to contribute to transcriptional regulation. Extensive transcriptomic dysregulation has been detected from postmortem brain samples of schizophrenia-affected individuals. However, the relationship between...
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