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Article

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.

Molecular psychiatry - 1 Feb 2012

Richards A L, Jones L, Moskvina V, Kirov G, Gejman P V, Levinson D F, Sanders A R, Purcell S, Visscher P M, Craddock N, Owen M J, Holmans P, O'Donovan M C

Abstract excerpt

It is widely thought that alleles that influence susceptibility to common diseases, including schizophrenia, will frequently do so through effects on gene expression. As only a small proportion of the genetic variance for schizophrenia has been attributed to specific loci, this remains an unproven hypothesis. The International Schizophrenia Consortium (ISC) recently reported a substantial polygenic contribution...

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Identifiers

PMID: 21339752
DOI: 10.1038/mp.2011.11
PMCID: PMC4761872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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