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Article

Mutation analysis of the TUBB8 gene in primary infertile women with arrest in oocyte maturation.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Oct 2018

Wang An-Cong, Zhang Yu-Song, Wang Bao-Song, Zhao Xiang-Yu, Wu Feng-Xia, Zhai Xiang-Hong, Sun Ju-Xiang, Mei Shi-Yue

Abstract excerpt

Tubulin beta eight class VIII (TUBB8) is a subtype of β-tubulin that only exists in primates. Mutations in the TUBB8 gene have been proven to cause oocyte maturation arrest. The aim of this study was to identify the new types of mutations in TUBB8. Six women (families) with oocyte maturation arrest and 100 healthy controls were recruited. The sequence of the TUBB8 gene was amplified and analyzed by Sanger...

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Source

Identifiers

PMID: 29671363
DOI: 10.1080/09513590.2018.1464138

Genes

TUBB8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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