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Clinical Application of CYP2C19 Pharmacogenetics Toward More Personalized Medicine

1 Jan 2013

Abstract excerpt

More than 30 years of genetic research on the CYP2C19 gene alone has identified approximately 2,000 reference single nucleotide polymorphisms (rsSNPs) containing 28 registered alleles in the P450 Allele Nomenclature Committee and the number continues to increase. However, knowledge of CYP2C19 SNPs remains limited with respect to biological functions. Functional information on the variant is essential for...

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PMID: 23378847
DOI: 10.3389/fgene.2012.00318

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