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Article

Correlation of TET2 SNP rs2454206 with improved survival in children with acute myeloid leukemia featuring intermediate-risk cytogenetics.

Genes, chromosomes & cancer - 1 Aug 2018

Wang Xingjuan, Chen Xi, Yang Zhenzhen, Dou Hu, Lu Ling, Bi Junqin, Zou Lin, Yu Jie, Bao Liming

Abstract excerpt

Single nucleotide polymorphisms (SNPs) may influence the disease course and outcome of hematologic neoplasms. SNP rs2454206 is common in the TET2 gene, which plays a role in epigenetic regulation of myelopoiesis. Few investigations examined the role of TET2 SNP rs2454206 in acute myeloid leukemia (AML) and none of those studies was performed in Chinese populations. Here, we report the prevalence and clinical...

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Source

Identifiers

PMID: 29664232
DOI: 10.1002/gcc.22540

Genes

TET2
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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