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Article

Prognostic significance of Tet methylcytosine dioxygenase 2 (TET2) gene mutations in adult patients with acute myeloid leukemia: a meta-analysis.

Leukemia & lymphoma - 1 Dec 2014

Liu Wen-Jian, Tan Xiao-Hong, Luo Xiu-Ping, Guo Bao-Ping, Wei Zhou-Ji, Ke Qing, He Sha, Cen Hong

Abstract excerpt

Tet methylcytosine dioxygenase 2 (TET2) gene mutations have recently been recognized in acute myeloid leukemia (AML). We performed a meta-analysis to evaluate the controversial prognostic significance of TET2 mutations in AML. Eight studies, covering 2552 patients with AML, were included in this analysis. Pooled hazard ratios (HRs) indicated that TET2 mutations had a poor prognostic impact on the survival of...

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Identifiers

PMID: 24524305
DOI: 10.3109/10428194.2014.893308

Genes

TET2
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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