Article
[Analysis of the Effect of TET2 Mutation and SNP on Clinical Characteristics and Prognosis of AML Patients].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2020
Li Li, An Li-Cai, Chu Xiao-Xia, Liu Xiao-Qian, Wang Lei
Abstract excerpt
OBJECTIVE: To evaluate the clinical significance of TET2 mutation(TET2mut) and SNP in adult acute myeloid leukemia (AML) and its effect on prognosis. METHODS: A total of 24 genes, including TET2, FLT3-ITD and NPM1, were detected in 124 adult AML patients using second-generation sequencing technology, and their clinical characteristics and effect on prognosis of patients were analyzed. RESULTS: A total of 25 TET2...
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