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The CpxA/CpxR Two-Component System Affects Biofilm Formation and Virulence in Actinobacillus pleuropneumoniae.

Frontiers in cellular and infection microbiology - 1 Jan 2018

Li Huan, Liu Feng, Peng Wei, Yan Kang, Zhao Haixu, Liu Ting, Cheng Hui, Chang Peixi, Yuan Fangyan, Chen Huanchun, Bei Weicheng

Abstract excerpt

Gram-negative bacteria have evolved numerous two-component systems (TCSs) to cope with external environmental changes. The CpxA/CpxR TCS consisting of the kinase CpxA and the regulator CpxR, is known to be involved in the biofilm formation and virulence of Escherichia coli. However, the role of CpxA/CpxR remained unclear in Actinobacillus pleuropneumoniae, a bacterial pathogen that can cause porcine contagious...

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Identifiers

PMID: 29662838
DOI: 10.3389/fcimb.2018.00072
PMCID: PMC5890194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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