Article
Role of the two-component regulator CpxAR in the virulence of Salmonella enterica serotype Typhimurium.
Infection and immunity - 1 Aug 2004
Humphreys Sue, Rowley Gary, Stevenson Andrew, Anjum Muna F, Woodward Martin J, Gilbert Stephen, Kormanec Jan, Roberts Mark
Abstract excerpt
The CpxAR (Cpx) two-component regulator controls the expression of genes in response to a variety of environmental cues. The Cpx regulator has been implicated in the virulence of several gram-negative pathogens, although a role for Cpx in vivo has not been demonstrated directly. Here we investigate whether positive or negative control of gene expression by Cpx is important for the pathogenesis of Salmonella...
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