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Article

BarA-UvrY two-component system regulates virulence of uropathogenic E. coli CFT073.

PloS one - 1 Jan 2012

Palaniyandi Senthilkumar, Mitra Arindam, Herren Christopher D, Lockatell C Virginia, Johnson David E, Zhu Xiaoping, Mukhopadhyay Suman

Abstract excerpt

Uropathogenic Escherichia coli (UPEC), a member of extraintestinal pathogenic E. coli, cause ∼80% of community-acquired urinary tract infections (UTI) in humans. UPEC initiates its colonization in epithelial cells lining the urinary tract with a complicated life cycle, replicating and persisting in intracellular and extracellular niches. Consequently, UPEC causes cystitis and more severe form of pyelonephritis....

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Identifiers

PMID: 22363626
DOI: 10.1371/journal.pone.0031348
PMCID: PMC3283629

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