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Article

[Mutation of the envelope stress-responsive protein CpxA capable of regulating the antimicrobial resistance and virulence of bacteria].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 25 Jul 2024

Xie Xueqin, Li Xinyao, Huang Jingyan, Xu Suneng, Chen Yiling, Qiu Yuhang, Tang Minchen, Xie Huilin, Deng Qiqi, Huang Jinghan

Abstract excerpt

CpxA is a key member of the envelope stress-responsive Cpx two-component system ubiquitous in Gram-negative bacteria. It is responsible for signal sensing and has dual activities of phosphatase and kinase. CpxA has been revealed to participate in the regulation of physiological processes such as virulence and antimicrobial resistance of bacteria. In recent years, the development of novel antimicrobials targeting...

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Identifiers

PMID: 39044573
DOI: 10.13345/j.cjb.240021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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