Article
New aspects of RpoE in uropathogenic Proteus mirabilis.
Infection and immunity - 1 Mar 2015
Liu Ming-Che, Kuo Kuan-Ting, Chien Hsiung-Fei, Tsai Yi-Lin, Liaw Shwu-Jen
Abstract excerpt
Proteus mirabilis is a common human pathogen causing recurrent or persistent urinary tract infections (UTIs). The underlying mechanisms for P. mirabilis to establish UTIs are not fully elucidated. In this study, we showed that loss of the sigma factor E (RpoE), mediating extracytoplasmic stress responses, decreased fimbria expression, survival in macrophages, cell invasion, and colonization in mice but increased...
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