Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus.

Nucleic acids research - 18 May 2018

Miyazono Ken-Ichi, Ishino Sonoko, Makita Naruto, Ito Tomoko, Ishino Yoshizumi, Tanokura Masaru

Abstract excerpt

Because base deaminations, which are promoted by high temperature, ionizing radiation, aerobic respiration and nitrosative stress, produce mutations during replication, deaminated bases must be repaired quickly to maintain genome integrity. Recently, we identified a novel lesion-specific endonuclease, PfuEndoQ, from Pyrococcus furiosus, and PfuEndoQ may be involved in the DNA repair pathway in Thermococcales of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Archaeal Proteins
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crystallography, X-Ray

Share to Endodeoxyribonucleases

Share to Metals

Share to Models, Molecular

Share to Protein Binding

Share to Pyrococcus furiosus

Source

Open in PubMed Open full text

Identifiers

PMID: 29660024
DOI: 10.1093/nar/gky261
PMCID: PMC5961232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus.PMID 29660024Read ↗

Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I.Semantic proximity Read ↗

Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.Semantic proximity Read ↗

The closed structure of an archaeal DNA ligase from Pyrococcus furiosus.Semantic proximity Read ↗

A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates.Semantic proximity Read ↗

Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddASemantic proximity Read ↗

Crystal structure of the NurA-dAMP-Mn2+ complex.Semantic proximity Read ↗

Functional interdependence of DNA polymerizing and 3'-->5' exonucleolytic activities in Pyrococcus furiosus DNA polymerase I.Semantic proximity Read ↗

Processing of A-form ssDNA by cryptic RNase H fold exonuclease PF2046.Semantic proximity Read ↗

The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast.Semantic proximity Read ↗

Aromatic residues located close to the active center are essential for the catalytic reaction of flap endonuclease-1 from hyperthermophilic archaeon Pyrococcus horikoshii.Semantic proximity Read ↗

UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB.Semantic proximity Read ↗

Coupling of the nucleotide incision and 3'-->5' exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.