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Article

Crystal structure of the NurA-dAMP-Mn2+ complex.

Nucleic acids research - 1 Mar 2012

Chae Jina, Kim Young Chang, Cho Yunje

Abstract excerpt

Generation of the 3' overhang is a critical event during homologous recombination (HR) repair of DNA double strand breaks. A 5'-3' nuclease, NurA, plays an important role in generating 3' single-stranded DNA during archaeal HR, together with Mre11-Rad50 and HerA. We have determined the crystal structures of apo- and dAMP-Mn(2)(+)-bound NurA from Pyrococcus furiousus (Pf NurA) to provide the basis for its cleavage...

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Identifiers

PMID: 22064858
DOI: 10.1093/nar/gkr999
PMCID: PMC3300031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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