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Article

Detection of in vivo hepatitis B virus surface antigen mutations-A comparison of four routine screening assays.

Journal of viral hepatitis - 1 Oct 2018

Gencay M, Seffner A, Pabinger S, Gautier J, Gohl P, Weizenegger M, Neofytos D, Batrla R, Woeste A, Kim H S, Westergaard G, Reinsch C, Brill E, Thuy P T T, Hoang B H, Sonderup M, Spearman C W, Brancaccio G, Fasano M, Gaeta G B, Santantonio T, Kaminski W E

Abstract excerpt

An important requirement for a state-of-the-art hepatitis B surface antigen (HBsAg) screening assay is reliable detection of mutated HBsAg. Currently, there is a striking shortage of data regarding the detection rates of in vivo HBsAg mutations for these clinically important assays. Therefore, we compared the detection rates of four commercial HBsAg screening assays using a global cohort of 1553 patients from...

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PMID: 29660206
DOI: 10.1111/jvh.12915

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