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Article

Genetic variation of hepatitis B surface antigen among acute and chronic hepatitis B virus infections in The Netherlands.

Journal of medical virology - 1 Oct 2018

Cremer Jeroen, Hofstraat Sanne H I, van Heiningen Francoise, Veldhuijzen Irene K, van Benthem Birgit H B, Benschop Kimberley S M

Abstract excerpt

Genetic variation within hepatitis B surface antigen (HBsAg), in particular within the major hydrophobic region (MHR), is related to immune/vaccine and test failures and can have a significant impact on the vaccination and diagnosis of acute infection. This study shows, for the first time, variation among acute cases and compares the amino acid variation within the HBsAg between acute and chronic infections. We...

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Identifiers

PMID: 29797607
DOI: 10.1002/jmv.25232
PMCID: PMC6120544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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