Article
[A study on the association of genes for pro-inflammatory cytokines and depression].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2000
Lezheiko T V, Andryushchenko A V, Korovaitseva G I, Kondratiev N V, Gabaeva M V, Krikova E V, Golimbet V E
Abstract excerpt
AIM: To study the association between proinflammatory cytokine genes and depression. MATERIAL AND METHODS: IL-1B С-511T and TNF-a G-308A gene polymorphisms were studied in patients diagnosed with depression and age and sex-matched healthy controls. RESULTS AND CONCLUSION: The IL-1B С-511T and TNF-a G-308A polymorphisms were associated with depression; CC genotype (р=0,001, OR=1.9 CI 1,3-2,7) and GG genotype...
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