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Article

A study of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ gene polymorphisms in patients with depression.

Journal of neuroimmunology - 15 Apr 2016

Mihailova Snezhina, Ivanova-Genova Elena, Lukanov Tzvetelin, Stoyanova Vesela, Milanova Vihra, Naumova Elissaveta

Abstract excerpt

In the last decade it was found that functional polymorphisms in the promoter and/or coding regions of regulatory genes are likely to pre-determine the phenotype manifestation of a certain cytokine profile, and thus could be used as disease-associated markers. Having in mind the hypothesis of impaired cytokine regulation in depressive disorder, as well as the diverse population-dependent results for cytokine...

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PMID: 27049572
DOI: 10.1016/j.jneuroim.2016.03.005

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TNF

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