Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physical health and incident late-life depression: modification by cytokine genes.

Neurobiology of aging - 1 Jan 2013

Kim Jae-Min, Stewart Robert, Kim Sung-Wan, Kim Seon-Young, Bae Kyung-Yeol, Kang Hee-Ju, Jang Ji-Eun, Shin Il-Seon, Yoon Jin-Sang

Abstract excerpt

Inflammatory cytokines have been implicated in the pathophysiology of depression, potentially underlying its association with worse physical health. Cytokine production is influenced by the transcriptional activity of several polymorphisms. We hypothesized that alleles related to higher proinflammatory and/or lower anti-inflammatory cytokine production would strengthen the association between physical disorders...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Genetic Association Studies

Share to Longitudinal Studies

Share to Residence Characteristics

Share to Statistics, Nonparametric

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 22921153
DOI: 10.1016/j.neurobiolaging.2012.01.111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physical health and incident late-life depression: modification by cytokine genes.PMID 22921153Read ↗

Genetic Contributions of Inflammation to DepressionSemantic proximity Read ↗

Associations of cytokine genes with Alzheimer's disease and depression in an elderly Korean population.Semantic proximity Read ↗

A one year longitudinal study of cytokine genes and depression in breast cancer.Semantic proximity Read ↗

The role of immune genes in the association between depression and inflammation: a review of recent clinical studies.Semantic proximity Read ↗

The role of pro-inflammatory cytokine gene polymorphisms in major depressive disorder: a systematic review.Semantic proximity Read ↗

The inflammatory cytokines: molecular biomarkers for major depressive disorder?Semantic proximity Read ↗

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depressionSemantic proximity Read ↗

Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.Semantic proximity Read ↗

Cytokine Genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and childhood-onset mood disorders.Semantic proximity Read ↗

A genetic predisposition to produce low levels of IL-10 is related to depressive symptoms: a pilot study of patients with end stage renal disease.Semantic proximity Read ↗

Interaction between cytokine gene polymorphisms and the effect of physical exercise on clinical and inflammatory parameters in older women: study protocol for a randomized controlled trial.Semantic proximity Read ↗

Proinflammatory Cytokines: A Common Denominator in Depression and Somatic Symptoms?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.