Article
Inflammation and depression.
Current topics in behavioral neurosciences - 1 Jan 2013
Zunszain Patricia A, Hepgul Nilay, Pariante Carmine M
Abstract excerpt
Major depressive disorder (MDD) is a complex illness and it is likely that alterations in several interacting systems underlie its pathogenesis. Numerous hypotheses have been proposed to elucidate its origins. The inflammatory hypothesis emphasises the role of psycho-neuroimmunological dysfunctions. This is based on several observations: subsets of MDD patients have an altered peripheral immune system, with...
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