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Article

A mega-analysis of expression quantitative trait loci in retinal tissue.

PLoS genetics - 1 Sept 2020

Strunz Tobias, Kiel Christina, Grassmann Felix, Ratnapriya Rinki, Kwicklis Madeline, Karlstetter Marcus, Fauser Sascha, Arend Nicole, Swaroop Anand, Langmann Thomas, Wolf Armin, Weber Bernhard H F

Abstract excerpt

Significant association signals from genome-wide association studies (GWAS) point to genomic regions of interest. However, for most loci the causative genetic variant remains undefined. Determining expression quantitative trait loci (eQTL) in a disease relevant tissue is an excellent approach to zoom in on disease- or trait-associated association signals and hitherto on relevant disease mechanisms. To this end,...

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Identifiers

PMID: 32870927
DOI: 10.1371/journal.pgen.1008934
PMCID: PMC7462281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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