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Article

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Nature - 1 Apr 2018

Liakath-Ali Kifayathullah, Mills Eric W, Sequeira Inês, Lichtenberger Beate M, Pisco Angela Oliveira, Sipilä Kalle H, Mishra Ajay, Yoshikawa Harunori, Wu Colin Chih-Chien, Ly Tony, Lamond Angus I, Adham Ibrahim M, Green Rachel, Watt Fiona M

Abstract excerpt

Ribosome-associated mRNA quality control mechanisms ensure the fidelity of protein translation1,2. Although these mechanisms have been extensively studied in yeast, little is known about their role in mammalian tissues, despite emerging evidence that stem cell fate is controlled by translational mechanisms3,4. One evolutionarily conserved component of the quality control machinery, Dom34 (in higher eukaryotes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29643507
DOI: 10.1038/s41586-018-0032-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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