Article

RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells.

2022-02-04

Abstract excerpt

<title>Abstract</title> <p>Embryonic stem cell (ESC) fate decisions are regulated by a complex molecular circuitry that requires tight and coordinated gene expression regulations at multiple levels from chromatin organization to mRNA processing. Recently, ribosome biogenesis and translation have emerged as key pathways that efficiently control stem cell homeostasis. However, the molecular mechanisms underlying th...

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Literature Corpus work: edb44da2-eeb4-5205-bc46-bfa368240194
DOI: 10.21203/rs.3.rs-738081/v1

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