Association of RETN and CAP1 SNPs, Expression and Serum Resistin Levels with Breast Cancer in Mexican Women.

doi:10.1089/gtmb.2017.0212

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Association of RETN and CAP1 SNPs, Expression and Serum Resistin Levels with Breast Cancer in Mexican Women.

Genetic testing and molecular biomarkers - 1 Apr 2018

Muñoz-Palomeque Alejandrina, Guerrero-Ramirez Miguel Angel, Rubio-Chavez Lidia Ariadna, Rosales-Gomez Roberto Carlos, Lopez-Cardona Maria Guadalupe, Barajas-Avila Victor Hugo, Delgadillo-Barrera Alfredo, Canton-Romero Juan Carlos, Montoya-Fuentes Hector, Garcia-Cobian Teresa Arcelia, Gutierrez-Rubio Susan Andrea

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer in women worldwide. Approximately 70% of female breast cancer patients have a body mass index (BMI) >25. In obesity, adipose tissue secretes additional resistin, which prompts a proinflammatory effect through its action on adenylate cyclase-associated protein 1 (CAP1). Several studies have associated the RETN gene single nucleotide polymorphism (SNP) rs1862513...

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PMID: 29641286
DOI: 10.1089/gtmb.2017.0212

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RETN

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