Article
Association of novel gene polymorphisms RRM1 -756T>C and -269 C>A with breast cancer.
Journal of clinical laboratory analysis - 1 Jul 2014
Chen Dar-Ren, Chuang Chun-Yi, Wu Buor-Chang, Yang Shun-Fa, Peng Yu-Hsien, Tsai Hsiu-Ting
Abstract excerpt
BACKGROUND: Genetic variants are reported to play an important role in the susceptibility of breast cancer. Ribonucleotide reductase 1 (RRM1) is suggested to play an essential role in the regulation of cancer development. The purpose of this study was to identify novel gene polymorphisms of RRM1 -756T>C and RRM1 -269 C>A specific to patients with breast cancer and healthy controls. METHODS: A total of 833...
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