Article
Plasma resistin is associated with single nucleotide polymorphisms of a possible resistin receptor, the decorin gene, in the general Japanese population.
Diabetes - 1 Feb 2013
Onuma Hiroshi, Tabara Yasuharu, Kawamura Ryoichi, Ohashi Jun, Nishida Wataru, Takata Yasunori, Ochi Masaaki, Nishimiya Tatsuya, Kawamoto Ryuichi, Kohara Katsuhiko, Miki Tetsuro, Osawa Haruhiko
Abstract excerpt
Resistin is an adipokine secreted from adipocytes in mice. We previously reported that a single nucleotide polymorphism (SNP) -420 (rs1862513) in the human resistin gene (RETN), is correlated with plasma resistin. Decorin is a multifunctional proteoglycan, and its isoform, lacking 14 amino acids from the N terminal region of mature core decorin, recently was identified as a resistin receptor in mice. To examine...
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