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Article

The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2009

Thaler Avner, Ash Elissa, Gan-Or Ziv, Orr-Urtreger Avi, Giladi Nir

Abstract excerpt

Mutations in the leucine rich repeat kinase 2 gene (LRRK2) are recognized as the most common cause of genetic Parkinsonism to date. The G2019S mutation has been implicated as an important determinant of Parkinson's disease (PD) in both Ashkenazi Jewish and North African Arab populations with carrier frequency of 29.7% among familial and 6% in sporadic Ashkenazi Jewish PD cases. PD patients with the G2019S...

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Identifiers

PMID: 19756366
DOI: 10.1007/s00702-009-0303-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews.PMID 19756366Read ↗

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