Article
Impact of Antiretroviral Regimens on Cerebrospinal Fluid Viral Escape in a Prospective Multicohort Study of Antiretroviral Therapy-Experienced Human Immunodeficiency Virus-1-Infected Adults in the United States.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 28 Sept 2018
Mukerji Shibani S, Misra Vikas, Lorenz David R, Uno Hajime, Morgello Susan, Franklin Donald, Ellis Ronald J, Letendre Scott, Gabuzda Dana
Abstract excerpt
Background: Cerebrospinal fluid (CSF) viral escape occurs in 4%-20% of human immunodeficiency virus (HIV)-infected adults, yet the impact of antiretroviral therapy (ART) on CSF escape is unclear. Methods: A prospective study of 1063 participants with baseline plasma viral load (VL) ≤400 copies/mL between 2005 and 2016. The odds ratio (OR) for ART regimens (protease inhibitor with nucleoside reverse transcriptase...
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