Article
Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: a systematic review.
AIDS reviews - 1 Jan 2000
Stam Arjen J, Nijhuis Monique, van den Bergh Walter M, Wensing Annemarie M J
Abstract excerpt
HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and is probably related to ongoing viral neuropathological processes. The central nervous system forms a distinct physiological, cellular, and pharmacological environment. We aimed...
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