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What can characterization of cerebrospinal fluid escape populations teach us about viral reservoirs in the central nervous system?

13 May 2019

Abstract excerpt

OBJECTIVE: To review the evidence that CSF (cerebrospinal fluid) escape populations are produced by viral reservoirs in the central nervous system (CNS). DESIGN: CSF escape is a rare phenomenon in which individuals on suppressive ART have well controlled systemic infections with elevated levels of HIV-1 RNA in their CSF. However, the rarity of CSF escape coupled with relatively low CSF viral loads has impeded...

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PMID: 31790378
DOI: 10.1097/qad.0000000000002253

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