Article
Tumor necrosis factor gene polymorphisms are associated with systemic lupus erythematosus susceptibility or lupus nephritis in Mexican patients.
Immunologic research - 1 Jun 2018
Ramírez-Bello Julian, Cadena-Sandoval Daniel, Mendoza-Rincón Jorge Flavio, Barbosa-Cobos Rosa Elda, Sánchez-Muñoz Fausto, Amezcua-Guerra Luis M, Sierra-Martínez Mónica, Jiménez-Morales Silvia
Abstract excerpt
The TNF -238G/A (rs361525) and -308G/A (rs1800629) polymorphisms have consistently been associated with systemic lupus erythematosus (SLE) in several populations; however, these findings have not been verified in all populations. Here, we aimed to examine whether the TNF -238G/A, -308G/A, -376G/A (rs1800750), and -1031T/C (rs1799964) polymorphisms confer SLE or lupus nephritis (LN) susceptibility in a Mexican...
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