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Article

TNF promoter -308 G>A and LTA 252 A>G polymorphisms in Portuguese patients with systemic lupus erythematosus.

Rheumatology international - 1 Aug 2012

Santos Maria José, Carmona-Fernandes Diana, Caetano-Lopes Joana, Perpétuo Inês P, Vidal Bruno, Capela Susana, Canas da Silva José, Fonseca João Eurico

Abstract excerpt

The polymorphism of the tumor necrosis factor (TNF) promoter gene at position -308 and that of the lymphotoxin alpha (LTA) gene at position 252 have been implicated as genetic risk factors for systemic lupus erythematosus (SLE) in some populations. In a nested case-control study, we investigated the possible association of these polymorphisms with susceptibility to SLE and with phenotypic disease features in...

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Source

Identifiers

PMID: 21544635
DOI: 10.1007/s00296-011-1950-7

Genes

LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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