Article
Tumor necrosis factor alpha promoter polymorphism -308 G/A in Brazilian patients with systemic lupus erythematosus.
Human immunology - 1 Nov 2012
Angelo Hildson Dornelas, da Silva Helker Albuquerque, Asano Nadja Maria Jorge, Muniz Maria Tereza Cartaxo, de Mascena Diniz Maia Maria, de Souza Paulo Roberto Eleutério
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of antibodies to components of the cell nucleus in association with a diverse array of clinical manifestations. Polymorphisms in cytokines genes may play an important role in the development and clinical manifestation. Due to this, there is a great interest in the identification of biomarkers that which could quantify the...
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