TNF-308 G/A polymorphism and risk of systemic lupus erythematosus in the Polish population.

doi:10.3109/14397595.2015.1008778

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TNF-308 G/A polymorphism and risk of systemic lupus erythematosus in the Polish population.

Modern rheumatology - 1 Sept 2015

Piotrowski Piotr, Wudarski Mariusz, Sowińska Anna, Olesińska Marzena, Jagodziński Paweł P

Abstract excerpt

OBJECTIVES: Numerous studies have been performed with TNF-α-308 G/A (rs1800629) single nuclear polymorphism (SNP) to evaluate the risk of SLE in various ethnicities. However, the significance of TNF-α-308 G/A in both clinical and laboratory studies of the disease remains unclear. METHODS: Using a high-resolution melting curve analysis, we assessed the prevalence of TNF-α-308 G/A SNP in SLE patients (n = 262) and...

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PMID: 25661739
DOI: 10.3109/14397595.2015.1008778

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