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Article

Population pharmacokinetics of voriconazole and CYP2C19 polymorphisms for optimizing dosing regimens in renal transplant recipients.

British journal of clinical pharmacology - 1 Jul 2018

Lin Xiao-Bin, Li Zi-Wei, Yan Miao, Zhang Bi-Kui, Liang Wu, Wang Feng, Xu Ping, Xiang Da-Xiong, Xie Xu-Biao, Yu Shao-Jie, Lan Gong-Bin, Peng Feng-Hua

Abstract excerpt

AIMS: The aims of the present study were to characterize the pharmacokinetics of voriconazole in renal transplant recipients and to identify factors significantly affecting pharmacokinetic parameters. We also aimed to explore the optimal dosing regimens for patients who developed invasive fungal infections. METHODS: A total of 105 patients (342 concentrations) were included prospectively in a population...

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Identifiers

PMID: 29607533
DOI: 10.1111/bcp.13595
PMCID: PMC6005582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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