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Population pharmacokinetics of voriconazole and CYP2C19 phenotype for dose optimization in hematological patients with invasive fungal infections

2022-11-21

Abstract excerpt

<h4>Aims: </h4> The aim of this study was to evaluate factors that impact on voriconazole trough concentration and explore the optimal dosing regimen of voriconazole for different CYP2C19 genotypes in a Chinese population. Methods Medical records of inpatients were reviewed retrospectively. Multivariate linear regression and population pharmacokinetic analysis was used to identify the factors contributing to the...

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Literature Corpus work
9f19de6a-2ce9-5f1f-9b69-4bee6a3c7962
DOI
10.21203/rs.3.rs-2270024/v1
Open publication

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