Article

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X Syndrome

2022-02-26

Abstract excerpt

The FMR1 gene is inactive in Fragile X syndrome (FXS), resulting in low levels of FMRP and consequent neurochemical, synaptic and local circuit neurophysiological alterations in the fmr1 KO mouse. In FXS patients, electrophysiological studies of have demonstrated a marked reduction in global alpha activity and regional increases in gamma oscillations that have been associated with intellectual disability and senso...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9e8ba98-8dc8-5cb5-aad7-f6eaed6cf935
DOI: 10.1101/2022.02.24.22271485

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X SyndromeDOI 10.1101/2022.02.24.22271485Read

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X SyndromeSemantic proximity Read

A human electrophysiological biomarker of Fragile X Syndrome is shared in V1 of <i>Fmr1</i> KO mice and caused by loss of FMRP in cortical excitatory neuronsSemantic proximity Read

Alpha oscillations are dysrhythmic in Fragile X syndromeSemantic proximity Read

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.Semantic proximity Read

Gaboxadol Increases Resting Theta and Alpha Power without Affecting Evoked Responses in Fragile X Syndrome in a Home-based SettingSemantic proximity Read

Validating brain activity measures as reliable indicators of individual diagnostic group and genetically mediated sub-group membership Fragile X SyndromeSemantic proximity Read

Increased aperiodic gamma power in young boys with Fragile X is associated with better language abilitySemantic proximity Read

Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome.Semantic proximity Read

Increased aperiodic gamma power in young boys with Fragile X Syndrome is associated with better language abilitySemantic proximity Read

Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J BackgroundSemantic proximity Read

Behavioral Phenotype Associations With Resting State EEG Signal Complexity and Power Spectral Density in Fragile X Syndrome.Semantic proximity Read

Electroencephalography signals in a female Fragile X Syndrome mouse modelSemantic proximity Read