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Article

Effect of Short-Term Antiretroviral Therapy Interruption on Levels of Integrated HIV DNA

29 Mar 2018

Abstract excerpt

ABSTRACT Analytic treatment interruption (ATI) studies are required to evaluate strategies aimed at achieving ART-free HIV remission, but the impact of ATI on the viral reservoir remains unclear. We validated a DNA size selection-based assay for measuring levels of integrated HIV DNA and applied it to assess the effects of short-term ATI on the HIV reservoir. Samples from participants from four AIDS Clinical...

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Identifiers

PMID: 29593048
DOI: 10.1128/jvi.00285-18

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