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Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials

25 Sept 2012

Abstract excerpt

OBJECTIVES: Interest in targeting HIV reservoirs is fueling trials that may decrease reservoir size and/or induce viral replication. Therefore, we aimed to develop strategies to sensitively measure changes in these parameters in patients on and off antiretroviral therapy (ART). Achieving these goals may help evaluate the effects of future clinical trials. DESIGN: To determine the relationship between measurements...

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PMID: 23014521
DOI: 10.1097/qad.0b013e32835a5c2f

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