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Article

Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth

3 Mar 2016

Abstract excerpt

The persistence of a reservoir of latently infected CD4 T cells remains one of the major obstacles to cure HIV. Numerous strategies are being explored to eliminate this reservoir. To translate these efforts into clinical trials, there is a strong need for validated biomarkers that can monitor the reservoir over time in vivo. A comprehensive study was designed to evaluate and compare potential HIV-1 reservoir...

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PMID: 26938995
DOI: 10.1371/journal.ppat.1005472

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