Article
Sparse Tensor Decomposition for Haplotype Assembly of Diploids and Polyploids.
BMC genomics - 21 Mar 2018
Hashemi Abolfazl, Zhu Banghua, Vikalo Haris
Abstract excerpt
BACKGROUND: Haplotype assembly is the task of reconstructing haplotypes of an individual from a mixture of sequenced chromosome fragments. Haplotype information enables studies of the effects of genetic variations on an organism's phenotype. Most of the mathematical formulations of haplotype assembly are known to be NP-hard and haplotype assembly becomes even more challenging as the sequencing technology advances...
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