Article
Alcohol consumption and early-onset risk of colorectal cancer in Japanese patients with Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Surgery today - 1 Aug 2018
Miguchi Masashi, Hinoi Takao, Tanakaya Kohji, Yamaguchi Tatsuro, Furukawa Yoichi, Yoshida Teruhiko, Tamura Kazuo, Sugano Kokichi, Ishioka Chikashi, Matsubara Nagahide, Tomita Naohiro, Arai Masami, Ishikawa Hideki, Hirata Keiji, Saida Yoshihisa, Ishida Hideyuki, Sugihara Kenichi
Abstract excerpt
We conducted this study to establish whether drinking alcohol alters the risk of early-onset colorectal cancer (CRC) in Japanese patients with Lynch syndrome (LS). The subjects were 66 LS patients with pathogenic mutation of mismatch repair genes (MLH1, MSH2, and MSH6) from the nationwide Japanese retrospective multicenter study. Cox proportional hazards modeling was used to investigate the factors correlating...
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