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Article

Efficient screening strategy for Lynch syndrome in Japanese endometrial cancer.

The Tohoku journal of experimental medicine - 1 Feb 2015

Sugawara Tae, Sato Naoki, Shimizu Dai, Sato Toshiharu, Makino Kenichi, Kito Masahiko, Tamura Daisuke, Kato Aya, Terada Yukihiro

Abstract excerpt

Lynch syndrome (LS) is an inherited disorder caused by a germline mutation in the DNA mismatch repair (MMR) genes and is associated with increased risk of various cancers, particularly colorectal cancer and endometrial cancer (EC). It is significant to identify LS in EC patients for prediction and prevention of the succeeding other associated cancers. However, useful LS screening guidelines for EC have not been...

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Source

Identifiers

PMID: 25745978
DOI: 10.1620/tjem.235.117

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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