Article
Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population.
Surgery today - 1 Jun 2016
Kumamoto Kensuke, Ishida Hideyuki, Suzuki Okihide, Tajima Yusuke, Chika Noriyasu, Kuwabara Koki, Ishibashi Keiichiro, Saito Katsuharu, Nagata Koji, Eguchi Hidetaka, Tamaru Junichi, Iwama Takeo
Abstract excerpt
PURPOSE: The aim of this study was to investigate the prevalence of Lynch syndrome among Japanese patients with surgically resected colorectal cancer at a single institution. METHODS: Of 616 colorectal cancer patients who underwent surgical operation in our institution from January 2005 to August 2010, immunohistochemistry analyses for mismatch repair proteins (MLH1, MSH2, MSH6, and PMS2) and microsatellite...
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