Article
Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients.
BMC gastroenterology - 30 Nov 2014
Miwata Tomohiro, Hiyama Toru, Quach Duc Trong, Le Huy Minh, Hua Ha Ngoc Thi, Oka Shiro, Tanaka Shinji, Arihiro Koji, Chayama Kazuaki
Abstract excerpt
BACKGROUND: The incidence of early-onset (under 50 years of age) colorectal cancer (CRC) in the Vietnamese has been reported to be quite higher than that in the Japanese. To clarify the differences in genetic alterations between Vietnamese and Japanese CRCs, we investigated mutations in K-ras and mitochondrial DNA (mtDNA) and high-frequency microsatellite instability (MSI-H) in the CRCs of Vietnamese and Japanese...
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