Article
C-reactive protein (CRP) polymorphisms and haplotypes are associated with SLE susceptibility and activity but not with serum CRP levels in Mexican population.
Clinical rheumatology - 1 Jul 2018
Atisha-Fregoso Yemil, Lima Guadalupe, Carrillo-Maravilla Eduardo, Posadas-Sánchez Rosalinda, Pérez-Hernández Nonanzit, Baños-Peláez Miguel, Iturralde-Chávez Alejandra, Hernández-Díaz Nora, Jakez-Ocampo Juan, Rodríguez-Pérez José Manuel, Vargas-Alarcón Gilberto, Llorente Luis, Romero-Díaz Juanita
Abstract excerpt
To evaluate the association of C-reactive protein (CRP) polymorphisms with risk of development SLE in a group of Mexican individuals. Five CRP polymorphisms (rs3093059, rs3093062, rs1800947, rs1130864, and rs1205) were determined by PCR-restriction fragment length polymorphism and SNP by refractory mutation system PCR assay in 126 SLE patients and 131 controls. Four of the polymorphisms showed...